Redox regulation of calcium ion channels: Chemical and physiological aspects
نویسندگان
چکیده
منابع مشابه
Redox regulation of calcium ion channels: chemical and physiological aspects.
Reactive oxygen species (ROS) are increasingly recognized as second messengers in many cellular processes. While high concentrations of oxidants damage proteins, lipids and DNA, ultimately resulting in cell death, selective and reversible oxidation of key residues in proteins is a physiological mechanism that can transiently alter their activity and function. Defects in ROS producing enzymes ca...
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SIGNIFICANCE The pulmonary circulation is a low-pressure, low-resistance, highly compliant vasculature. In contrast to the systemic circulation, it is not primarily regulated by a central nervous control mechanism. The regulation of resting membrane potential due to ion channels is of integral importance in the physiology and pathophysiology of the pulmonary vasculature. RECENT ADVANCES Redox...
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ژورنال
عنوان ژورنال: Cell Calcium
سال: 2011
ISSN: 0143-4160
DOI: 10.1016/j.ceca.2011.07.006